Disorders of Gut-Brain Interaction (DGBI), also known as Functional Gastrointestinal Disorders (FGID), represent a significant burden to the UK and global healthcare.
DGBI are the most common diagnosis in gastroenterology, comprising a complex and incompletely understood group of over 30 chronic conditions, including irritable bowel syndrome (IBS), chronic constipation, functional diarrhoea, functional dysphagia, functional dyspepsia, and functional abdominal pain, and more. Triggers include diet, food sensitivity, stress and lifestyle. The autonomic nervous system (ANS) and stress are involved in most conditions.
A recent large-scale study (over 70,000 participants in 33 countries; 6 continents) found that more than 40% of persons worldwide have DGBI, which affects the quality of life and health care use. This equates to over 2 billion sufferers globally.
DGBI affects both sexes but is much more prevalent among women, representing a significant issue for women’s health.